Comparison of Multiple Oxygenation Targets With Different Oximeters in Chronic Obstructive Pulmonary Disease (COPD) and Non-COPD Patients- Impact on Oxygen Flows

N/AUnknownNCT05819164

Laval University40 enrolled

Overview

The oximeter is an instrument for monitoring patients receiving oxygen therapy. It displays pulse oxygen saturation (SpO2), which is a reflection of arterial oxygen saturation (SaO2). An accurate SpO2 value is essential for optimal management of the O2 flow delivered to patients. Several factors can influence this measurement and the choice of ventilatory support: the type of oximeter used, skin pigmentation and the oxygenation goal. The objective of our study is to evaluate the impact of the oxygenation goal and the oximeter used on oxygen flows in patients with COPD (or with hypercapnia, or at risk of hypercapnia) and in patients without COPD (in particular pneumonia, pulmonary fibrosis and other pathologies) Our hypothesis is that the SpO2 target and oximeter used will have an impact on oxygen flows and that these effects will be synergistic in these different populations.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

COPD Exacerbation Pneumonia Hypoxemia Respiratory Disease

Interventions

Masimo oximeterDEVICE

During this period, the Masimo oximeter Radical 7 was used for SpO2 reading

Nellcor oximeterDEVICE

During this period, the Nellcor oximeter N-600 was used for SpO2 reading

Nonin oximeterDEVICE

During this period, the Nonin oximeter was used for SpO2 reading

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ≥ 18 years old * On conventional oxygen therapy with SpO2 between 88 and 100% with the usual oximeter and nasal cannula. * SpO2 \< 92% in ambient air with the usual oximeter Exclusion Criteria: * No availability of the SpO2 signal with the usual oximeter * False nails or nail polish * Severe anemia documented on the last blood count during the current hospitalization (Hb \< 80g/L)

Outcomes

Primary Outcomes

Oxygen flow

the mean oxygen flow to reach the SpO2 target +/- 1% during 2 minutes for each period and each oximeter

Time frame: assessed up to 10 minutes

Secondary Outcomes

Partial oxygen weaning

Rate of partial oxygen weaning (Oxygen flow \<=0.5 L/min) to reach the SpO2 target for each period and each oximeter

Time frame: assessed up to 10 minutes - until SpO2 target stability for 2 minutes

Complete oxygen weaning

Rate of complete oxygen weaning (Oxygen flow \<=0.1 L/min) to reach the SpO2 target for each period and each oximeter

Time frame: assessed up to 10 minutes - until SpO2 target stability for 2 minutes

High oxygen flow

Rate of high oxygen flow (Oxygen flow \>5.0 L/min) to reach the SpO2 target for each period and each oximeter

Time frame: assessed up to 10 minutes - until SpO2 target stability for 2 minutes

Oximeter bias comparison

the mean bias between the result of the different oximeter

Time frame: assessed up to 10 minutes - until SpO2 target stability for 2 minutes

Comparison of Multiple Oxygenation Targets With Different Oximeters in Chronic Obstructive Pulmonary Disease (COPD) and Non-COPD Patients- Impact on Oxygen Flows

Overview

Conditions

Interventions

Eligibility

Outcomes

Primary Outcomes

Secondary Outcomes

Central Contacts