To investigate the feasibility of a combined OCT/FLIM device
To investigate the feasibility of a combined Optical coherence tomography/ Fluorescence Lifetime Measurement (OCT/FLIM) device.
Study Type
OBSERVATIONAL
Enrollment
70
OCT/FLIM imaging of the retina
Department of Ophthalmology, Bern University Hospital, Bern, 3010 Bern, Switzerland
Bern, Switzerland
Feasibility of device
We will organize and perform an observational study with the prototype OCT+FLIM device and contribute the acquired OCT/FLIM datasets from eyes of different age and status of the crystalline lens.
Time frame: 1 year
To provide two key technology aspects of the project:
A. The first will be to bring forward a novel registration strategy for calibrated OCT and FLIM modalities, so that these can be used in conjunction. B. The second will be to develop an image calibration and normalization method using the measured lens fluorescence lifetime and possibly also structural (OCT) information on lens and retina, so that data acquired by the device can be used across different patients in a consistent way.
Time frame: 1 year
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