The goal of this randomized controlled study is to guide volumetric rejuvenation on dorsal hands with the maximal aesthetic appearance. The main questions it aims to answer are: * Which fatty layer(s) is/are the most suitable for filler injection? * Is it feasible to make precise filler injections with sonography guidance? Participants will receive sonography-guided injection on the one hand and another with blinded injection.
In our previous study, volumetric fat loss was noted in the 3 fatty laminae of dorsal hands during aging; the dorsal intermediate lamina (DIL) showed the greatest progressive fat loss after the age of 30. Volumetric rejuvenation of the 3 laminae may result in the most aesthetic appearance, especially in women. It is necessary to develop precise rejuvenation therapies according to the aging process of the dorsum of the hands that will yield the most aesthetic appearance.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
200
Volumetric Rejuvenation with FDA-approved fillers on the skin of the dorsal hands
Ocean Clinic Marbella
Marbella, Spain
RECRUITINGChang Gung Memorial Hospital
Taoyuan, Taiwan
RECRUITINGAesthetic improvement
5-point global aesthetic improvement scales scoring (Min:1; Max:5)
Time frame: Day 0, 30, 180 follow up
Thickness of the fatty laer
Thickness of the dorsal superficial lamina (DSL) and dorsal intermediate lamina (DIL)
Time frame: Day 0, 30, 180 follow up
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