The goal of this single center prospective controlled observational and interventional trial is to investigate and compare origin of air emboli when different venous cannulation methods is used in patients undergoing cardiac surgery with extracorporeal circulation. 40 consecutive elective patients will be included in two groups, depending on the procedure requiring bicaval or cavoatrial cannulation. After assorted into respective group, patients will be block randomized (five groups consisting of eight patients each) to either intervention group (low venous reservoir volume, 200-300 mL) or control group (venous reservoir volume \> 300 mL). Primary endpoint is to investigate if the amount of air emboli passing through the oxygenator to the arterial line differs between bicaval and cavoatrial venous cannulation during extracorporeal circulation. Secondary endpoints are the relative difference in amount air emboli between the groups, if there is any correlation between the amount of air in venous line and the amount of air passing through the oxygenator to the arterial line during extracorporeal circulation, and if difference is seen on the amount of air passing through the oxygenator depending on the level of volume in the venous reservoir.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
40
Volume control in venous reservoir during extracorporeal circulation.
Department of Cardiothoracic Surgery, Perfusion. Sahlgrenska University Hospital.
Gothenburg, Västra Götaland County, Sweden
Difference in count (number) of air emboli passing through the oxygenator to the arterial line between bicaval and cavoatrial venous cannulation.
Bubble counter measurements
Time frame: 1 day (During extracorporeal circulation)
Difference in volume (nano liter) of air emboli passing through the oxygenator to the arterial line between bicaval and cavoatrial venous cannulation.
Bubble counter measurements
Time frame: 1 day (During extracorporeal circulation)
Difference in the amount of air emboli in venous tubing between bicaval and cavoatrial cannulation.
Bubble counter measurements
Time frame: 1 day (During extracorporeal circulation)
Correlation between the amount of air in venous line and the amount of air passing through the oxygenator to the arterial line during extracorporeal circulation.
Bubble counter measurements
Time frame: 1 day (During extracorporeal circulation)
Difference in amount of air passing through the oxygenator depending on the volume in the venous reservoir (200-300 mL versus > 300 mL).
Bubble counter measurements
Time frame: 1 day (During extracorporeal circulation)
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