48 adult patients participated in a single-centre randomized clinical trial with split- mouth design. They had presented at re-evaluation after initial non-surgical periodontal therapy (steps 1 and 2 of periodontal therapy) for generalized periodontitis with at least 2 teeth with residual probing pocket depths (PPD) ≥5 and ≤8 mm, with bleeding on probing (BOP). Two teeth with similar PPD were randomized to receive re-instrumentation either with (test) or without (control) adjunctive flapless administration of EMD. Differences in the changes of PPD and BOP from baseline to 6 and 12 months will be analysed, and the frequencies of pocket closure (PPD ≤4 mm and no BOP) will be compared
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
48
Teeth with deep probing pocket depths were randomized to receive re-instrumentation with adjunctive flapless administration of EMD
Teeth with deep probing pocket depths were randomized to receive re-instrumentation with adjunctive placebo application
Arab American University
Ramallah, Palestinian Territories
Differences in changes of probing pocket depths (PPD) from baseline to 6 and 12 months
probing pocket depth (PPD)
Time frame: 12 months
Differences in changes of bleeding on probing (BOP) from baseline to 6 and 12 months
bleeding on probing (BOP)
Time frame: 12 months
frequencies of pocket closure
PPD ≤4 mm
Time frame: 12 months
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