This is a single center prospective study to compare the short term results of prosthesis, nail and plate-screw surgeries for metastatic pathologic fractures.
The most common bone tumor in elderly is metastatic bone tumors. With the prolonged life expectancy in cancer patients, the management of the metastases became an essential topic. Pathological fractures should be examined and managed with a different perspective. They usually cannot be healed by conservative methods and require surgical intervention. The primary goals of surgical intervention are to relieve pain and mobilize the patient as soon as possible. The aim of the study is to compare the short-term functional endoprosthetic recontruction, intramedullary nailing and open reduction internal fixation. The primary tumor of the patient, applied chemotherapy and radiotherapy, Mirel risk score, Charlson comorbidity index, and PathFx 3.0 survival will be evaluated preoperatively. The type of the operation will be decided at the multidisciplinary tumor council of ankara University.
Study Type
OBSERVATIONAL
Enrollment
200
This is a type of surgery in which the affected part of the bone and joint is removed, and replaced by a prosthesis.
This is a type of surgery in which the affected bone is stabilized by a nail. The affected part could be removed or retained. If removed, the defect is filled with bone cement.
This is a type of surgery in which the affected part of the bone is visualized completely, after the reduction is achieved, the fixation is provided with appropriate plates and screws. Again the affected part could be removed or retained. If removed, the defect is filled with bone cement.
Ankara University Medical Faculty
Ankara, altindag, Turkey (Türkiye)
RECRUITINGMusculoskeletal Tumor Society (MSTS) score
MSTS score is for evaluating the patients with bone tumors. It consists of six domains; scored on a 0 to 5 scale and transformed into an overall score ranging from 0 to 100% with a higher score indicating better function.
Time frame: Preoperative
Musculoskeletal Tumor Society (MSTS) score
MSTS score is for evaluating the patients with bone tumors. It consists of six domains; scored on a 0 to 5 scale and transformed into an overall score ranging from 0 to 100% with a higher score indicating better function.
Time frame: Postoperative 1st day
Musculoskeletal Tumor Society (MSTS) score
MSTS score is for evaluating the patients with bone tumors. It consists of six domains; scored on a 0 to 5 scale and transformed into an overall score ranging from 0 to 100% with a higher score indicating better function.
Time frame: Postoperative 1st week
Musculoskeletal Tumor Society (MSTS) score
MSTS score is for evaluating the patients with bone tumors. It consists of six domains; scored on a 0 to 5 scale and transformed into an overall score ranging from 0 to 100% with a higher score indicating better function.
Time frame: Postoperative 1st month
Toronto Extremity Salvage Score (TESS)
TESS is widely used for the functional assessment of patients following surgery for musculoskeletal tumours. In the TESS system, specific movements for independent living and functionality are questioned and scored.While the worst score is 0, the best score for the lower extremity is 150, and the best score for the upper extremity is 145.
Time frame: Preoperative
Toronto Extremity Salvage Score (TESS)
TESS is widely used for the functional assessment of patients following surgery for musculoskeletal tumours. In the TESS system, specific movements for independent living and functionality are questioned and scored.While the worst score is 0, the best score for the lower extremity is 150, and the best score for the upper extremity is 145.
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Time frame: Postoperative 1st day
Toronto Extremity Salvage Score (TESS)
TESS is widely used for the functional assessment of patients following surgery for musculoskeletal tumours. In the TESS system, specific movements for independent living and functionality are questioned and scored.While the worst score is 0, the best score for the lower extremity is 150, and the best score for the upper extremity is 145.
Time frame: Postoperative 1st week
Toronto Extremity Salvage Score (TESS)
TESS is widely used for the functional assessment of patients following surgery for musculoskeletal tumours. In the TESS system, specific movements for independent living and functionality are questioned and scored.While the worst score is 0, the best score for the lower extremity is 150, and the best score for the upper extremity is 145.
Time frame: Postoperative 1st month
Visual analog scale (VAS)
VAS is a widely used scale for pain. 0 means no pain where 10 means unbearable pain.
Time frame: Preoperative
Visual analog scale (VAS)
VAS is a widely used scale for pain. 0 means no pain where 10 means unbearable pain.
Time frame: Postoperative 1st day
Visual analog scale (VAS)
VAS is a widely used scale for pain. 0 means no pain where 10 means unbearable pain.
Time frame: Postoperative 1st week
Visual analog scale (VAS)
VAS is a widely used scale for pain. 0 means no pain where 10 means unbearable pain.
Time frame: Postoperative 1st month
Upper Extremity Functional Scale (UEFS)
UEFS is a functional scale for upper extremity. It is not specific for tumor patients.
Time frame: Preoperative
Upper Extremity Functional Scale (UEFS)
UEFS is a functional scale for upper extremity. It is not specific for tumor patients.
Time frame: Postoperative 1st day
Upper Extremity Functional Scale (UEFS)
UEFS is a functional scale for upper extremity. It is not specific for tumor patients.
Time frame: Postoperative 1st week
Upper Extremity Functional Scale (UEFS)
UEFS is a functional scale for upper extremity. It is not specific for tumor patients.
Time frame: Postoperative 1st month
Disabilities of Arm, Shoulder and Hand (DASH)
DASH is a widely used functional scale for upper extremity. It is not specific for tumor patients.
Time frame: Preoperative
Disabilities of Arm, Shoulder and Hand (DASH)
DASH is a widely used functional scale for upper extremity. It is not specific for tumor patients.
Time frame: Postoperative 1st day
Disabilities of Arm, Shoulder and Hand (DASH)
DASH is a widely used functional scale for upper extremity. It is not specific for tumor patients.
Time frame: Postoperative 1st week
Disabilities of Arm, Shoulder and Hand (DASH)
DASH is a widely used functional scale for upper extremity. It is not specific for tumor patients.
Time frame: Postoperative 1st month
Lower Extremity Functional Scale (LEFS)
LEFS is a functional scale for lower extremity. It is not specific for tumor patients.
Time frame: Preoperative
Lower Extremity Functional Scale (LEFS)
LEFS is a functional scale for lower extremity. It is not specific for tumor patients.
Time frame: Postoperative 1st day
Lower Extremity Functional Scale (LEFS)
LEFS is a functional scale for lower extremity. It is not specific for tumor patients.
Time frame: Postoperative 1st week
Lower Extremity Functional Scale (LEFS)
LEFS is a functional scale for lower extremity. It is not specific for tumor patients.
Time frame: Postoperative 1st month
Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)
WOMAC is a widely used functional scale for lower extremity. It is not specific for tumor patients.
Time frame: Preoperative
Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)
WOMAC is a widely used functional scale for lower extremity. It is not specific for tumor patients.
Time frame: Postoperative 1st day
Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)
WOMAC is a widely used functional scale for lower extremity. It is not specific for tumor patients.
Time frame: Postoperative 1st week
Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)
WOMAC is a widely used functional scale for lower extremity. It is not specific for tumor patients.
Time frame: Postoperative 1st month
Days at hospital after surgery
Hospitalization length required after the surgery.
Time frame: up to 1 month
Survival
Time that the patient lives after the surgery
Time frame: up to 3 months