Multicenter Retrospective Study of Isoflurane in Refractory and Super-Refractory Status Epilepticus

Hopital of Melun66 enrolled

Overview

Isoflurane might be used as anticonvulsive therapy in refractory status epilepticus. The aim of the study is to assess the efficiency of Isoflurane in this indication.

Investigators will collect in 4 ICUs the data from consecutive patients hospitalized between january 2016 and january 2023. Included patient were those treated by Isoflurane for refractory status epilepticus.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Refractory Status Epilepticus

Interventions

IsofluraneDRUG

no other intervention

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age \> 18 years, hospitalized in ICU between 2016-01-01 and 2023-01-01, suffering refractory status epilepticus treated by inhaled Isoflurane as third anticonvulsive therapy Exclusion Criteria: * post-anoxic refractory status epilepticus after cardiac arrest, withdrawal of consent for medical data use

Locations (4)

Ch Bethune Beuvry

Beuvry, France

CHU Brest

Brest, France

GH Sud Ile de France, Hôpital de Melun-Sénart

Melun, France

CH Toulon - Sainte Musse

Toulon, France

Outcomes

Primary Outcomes

rate of crisis control

rate of patients with crisis control or complete awakening

Time frame: 3 months

Data from ClinicalTrials.gov

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