Evaluation of Dental Maturation and Mandibular Bone Morphology in Childhood Rheumatic Diseases

Marmara University278 enrolled

Overview

The aim of our study is to examine possible disease-related changes in dental age and mandibular bone morphology in childhood rheumatic diseases.

to reveal the changes that can occur in different childhood rheumatic diseases, the treatment process of the disease and the drugs used on the dental age and mandible

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SCREENING

Masking

SINGLE

Enrollment

278

Conditions

Childhood Rheumatic Diseases

Interventions

Panoramic rad.RADIATION

In the study, digital panoramic x-rays of the patients will be evaluated and dental age estimation with Willems method and mandibular bone morphometric measurements will be made.

Eligibility

Sex: ALLMin age: 6 YearsMax age: 14 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients aged 6 to 14 years with childhood rheumatism * Patients without bilateral congenital germ deficiency in the lower teeth * Patients with seven teeth (except no #8) on the left of the mandibula (No seven teeth on the left of the mandibula, there should be a symmetrical tooth on the right of the mandibula. Exclusion Criteria: * Patients with bilateral congenital germ deficiency in lower teeth in intraoral and/or radiographic examinations * Patients with asymmetry and magnification errors and where anatomical structures cannot be seen clearly in the panoramic x-ray * Patients with a significant number of missing teeth due to trauma or disease, root canal treatment, and pathological tooth structure * Patients with a history of other chronic diseases

Locations (1)

Ecem Ipek

Istanbul, Turkey (Türkiye)

Outcomes

Primary Outcomes

Dental Age Estimation

Time frame: 3 months

Secondary Outcomes

Mandibular bone morphometric measurements

The study group will be comprised of newly diagnosed pediatric patients who applied to Umraniye Training and Research Hospital Division of Pediatric Rheumatology and whose treatment is ongoing, and the control group will be composed of pediatric patients without systemic disease who applied to Marmara University Faculty of Dentistry Department of Pedodontics.For mandibular bone morphometric measurements, fractal analysis, that is a mathematical method describing and analyzing complex shapes and structural patterns such as the bone tissue, will be used in order to assess the bone density, using Image J software. A region of interest will be selected from panoramic radiographs. Image processing will be applied to correct for lightning irregularity, and box-counting method will be used to calculate a fractal dimension.

Time frame: 3 months

Data from ClinicalTrials.gov

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