Cool vs Room-temperature Artificial Tears

University of Iowa124 enrolled

Overview

Background and Objective: To evaluate the efficacy of cooled versus room temperature artificial tears in reducing post intravitreal injection (IVI) ocular discomfort. Patients and Methods: Patients receiving IVI were randomized to either cooled or room temperature tears intervention groups. Both groups rated their ocular discomfort following IVI before intervention and again after administration of cooled or room temperature tears.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

124

Conditions

Diabetic Retinopathy With Macular Edema of Both Eyes (Diagnosis)Central Retinal Vein Occlusion With Macular Edema Exudative Age-Related Macular Degeneration, Unspecified Eye Cystoid Macular Edema

Eligibility

Sex: ALLMin age: 18 YearsMax age: 105 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients were eligible if they were receiving standard intravitreal injections for their exudative age-related macular degeneration, cystoid macular edema, diabetic macular edema, proliferative diabetic retinopathy, retinal vein occlusion with macular edema, or retinal neovascularization. Exclusion Criteria: * Inability or lack of willingness to participate in the study * Active ocular infection including infectious uveitis * First time receiving intravitreal injection * Those who reported never having ocular discomfort following intravitreal injections on the pre-injection questionnaire * Less than 18 years of age

Outcomes

Primary Outcomes

The Efficacy of Cooled Versus Room Temperature Artificial Tears in Reducing Post Intravitreal Injection Ocular Discomfort as Measured by Pain Scale Survey.

The level of subjectively reported pain scale from 1 to 10, where 1 is minimal pain and 10 is extreme pain

Time frame: with 72 hours of the intervention