Magnetoencephalography by Optical Pumping Magnetometer

Centre Hospitalier Universitaire, Amiens70 enrolled

Overview

MagnetoEncephaloGraphy (MEG) is a method of recording brain activity with high temporal resolution and good spatial resolution, compared to current recording techniques such as ElectroEncephaloGraphy (EEG). The main limitation of MEG is its cost due to the sensors used, the Super Quantum Interference Devices (SQUID). These require a complex infrastructure from an instrumentation point of view to operate, requiring liquid helium, most often at a loss, at increasing cost. Optical Pumping Magnetometers (OPM) type sensors represent a promising alternative to SQUIDs sensors, especially since they do not require helium cooling. The purpose of this project is to Identify biomarkers in Magnetoencephalography of normal brain development in healthy adults, premature and term newborns from "a priori" obtained by the classical technique of High Resolution EEG performed.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

OTHER

Masking

SINGLE

Enrollment

Conditions

Magnetoencephalography Optical Pump Magnetometer Neonate

Eligibility

Sex: ALLMin age: 1 DayHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * For healthy adult volunteers * Age between 18 and 65 * No pathology, no treatment * No toxicant intake * For term newborns * Child between 38 and 42 weeks gestational age on the day of registration * No pathology, no treatment * For children born prematurely * Child between 28 and 36 weeks gestational age on the day of registration * No pathology, no treatment apart from routine care related to prematurity * For pregnant women * Pregnant with between 28 to 40 weeks gestational age on the day of registration * No pathology, no treatment Exclusion Criteria: * Subject and Patients "not compatible" MEG. Wearers of prosthesis or pacemaker likely to generate artefacts interfering with the measurement. There is no danger to the subject, but the measurement itself may be impossible. * Patients who cannot stand to stand still for a few minutes. * Newborn on ventilatory assistance or infusion * Newborn baby not meeting the age criteria

Outcomes

Primary Outcomes

Signal to noise ratio of the MEG OPM

Signal to noise ratio of the MEG OPM is in dB

Time frame: 1 day

Signal to noise ratio of HR EEG

Signal to noise ratio of HR EEG is in dB

Time frame: 1 day

Number of dB between Signal to noise ratio of the MEG OPM and Signal to noise ratio of HR EEG

Time frame: 1 day

Magnetoencephalography by Optical Pumping Magnetometer

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Central Contacts