Because Propofol is the primary "anesthetic agent," and inhalational agents remain in trace quantities at the end of the procedure Sevoflurane initiated intravenous anesthesia (SIIVA) or not present at all Total intravenous anesthesia (TIVA) it is likely that different criteria may be predictive of extubation success in these patients compared to inhalational anesthesia.
This is because these anesthetic regimens have different pharmacologic mechanisms of actions, and therefore interact with central nervous system in different ways leading to potentially the need for different extubation criteria in patients receiving TIVA or SIIVA. Additionally, intravenous agents likely have less of an effect on airway reflexes and ventilation at light levels of anesthesia. This study is proposing an observational study to examine the predictive value of various extubation criteria in the setting of SIIVA and TIVA.
Study Type
OBSERVATIONAL
Enrollment
600
TIVA anesthetic -no inhalational gases for surgery
SIIVA - sevoflurane anesthetic gases for surgery
Atrium Health Wake Forest Baptist
Winston-Salem, North Carolina, United States
RECRUITINGPerth Children's Hospital
Perth, Australia
NOT_YET_RECRUITINGExtubation success rate
quality of extubation will be assess using a standard rubric for all extubation
Time frame: Day 1
Rate of extubation that requiring intervention
desaturation, laryngospasm, airway obstruction or other issues
Time frame: Day 1
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