Study of Two Digital Therapeutics for the Treatment of Experiential Negative Symptoms of Schizophrenia

Motivation and pleasure symptoms

Change from baseline in motivation and pleasure symptoms at Week 8, as assessed by CAINS-MAP

Time frame: Baseline to Week 8

Expressive negative symptoms

Change from baseline in expressive negative symptoms at Weeks 8 and 16, as assessed by the Clinical Assessment Interview for Negative Symptoms, Expressivity Scale (CAINS-EXP)

Time frame: Baseline to Weeks 8 and 16

Positive symptoms

Change from baseline in positive symptoms at Weeks 8 and 16, as assessed by the Positive and Negative Syndrome Scale (PANSS)

Time frame: Baseline to Weeks 8 and 16

Social functioning

Change from baseline in social functioning at Weeks 8 and 16, as assessed by the Personal and Social Performance Scale (PSP)

Time frame: Baseline to Weeks 8 and 16

Self-reported defeatist beliefs

Change from baseline in self-reported defeatist beliefs at Weeks 8 and 16, as assessed by the Defeatist Beliefs Subscale of the Dysfunctional Attitudes Scale (DAS)

Time frame: Baseline to Weeks 8 and 16

Patient global impression of improvement

Patient Global Impression of Improvement Scale (PGI-I) at Weeks 8 and 16