Primary Tumor Burden Score:A Novel Staging Parameter for ESCC After nCRT

Fudan University187 enrolled

Overview

In this case-only study, the investigators try to define a novel staging parameter, the Primary Tumor Burden Score (PTBS).

In this case-only study, the investigators try to define a novel staging parameter, the Primary Tumor Burden Score (PTBS), which will combine the proportion of residual primary tumor cells and pre-treatment pathological T stage (prepT stage). The investigators will also try to improve ypTNM stage by results of PTBS.

Study Type

OBSERVATIONAL

Enrollment

187

Conditions

Neoplasm, Esophagus Neoplasm, Squamous Cell

Interventions

nCRTPROCEDURE

ESCC patients that recieved surgery and nCRT.

Eligibility

Sex: ALLMin age: 40 YearsMax age: 79 Years

Medical Language ↔ Plain English

Inclusion Criteria: \- Neoadjuvant chemoradiotherapy and surgical resection of esophageal squamous cell carcinoma Exclusion Criteria: * Patients receiving neoadjuvant chemoradiotherapy for esophageal squamous cell carcinoma without surgical resection

Outcomes

Primary Outcomes

Five-year survival of patients

The survival of the patients was recorded by follow-up for five years after surgery.

Time frame: From surgery to the end of follow-up(at least 5 years later)

Data from ClinicalTrials.gov

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