The purpose of this study is to identify the effects of non-pharmacological and pharmacological anti-hypotensive treatment interventions on orthostatic hemodynamic responses, symptoms of autonomic dysreflexia and orthostatic hypotension, and levels of fatigue and comfort in hypotensive individuals with SCI.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
25
Determine best drug and dose to increase and stabilize SBP during orthostatic tilt
Kessler Foundation
West Orange, New Jersey, United States
RECRUITINGJames J Peters VA Medical Center
The Bronx, New York, United States
RECRUITINGSystolic blood pressure
determine differences in systolic blood pressure after midodrine, droxidopa, compression stockings and placebo
Time frame: 3 years
Cerebral blood flow velocity
determine differences in cerebral blood flow velocity after midodrine, droxidopa, compression stockings and placebo
Time frame: 3 years
Symptoms of autonomic dysreflexia and orthostatic hypotension
determine differences in symptoms after midodrine, droxidopa, compression stockings and placebo
Time frame: 3 years
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