DEXMEDETOMIDINE in NORMAL VAGINAL DELIVERY

Menoufia University60 enrolled

Overview

compare the effect of intravenous and epidural dexmetomidine as an adjuvant to local anesthetics in epidural labor analgesia in normal labor

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

DOUBLE

Enrollment

Conditions

Painless Vainal Labour

Interventions

Dexmedetomidine Injection [Precedex]DRUG

interventional drug will be administred either intravenously or epidurally

Bupivacaine InjectionDRUG

intervention drug will be administred epidurally

Eligibility

Sex: FEMALEMin age: 19 YearsMax age: 30 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Full term (≥ 37 weeks) healthy primigravida parturients ASA2 * with single fetus scheduled for vaginal delivery * with cephalic presentation * requesting labor analgesia. Exclusion Criteria: * Allergy to dexmetomidine.(based on previous history) * Cardiac conduction abnormalities.(all degrees of heart block , tachyarrythmias) * Twins. * Malpresentation. * Preeclampsia or gestational hypertension * Uncontrolled diabetes HBA1c ≥ 6.5% * Uncontrolled renal failure * Uncontrolled liver disease * Bleeding tendency or coagulopathy. * Contraindication or patient refusal to epidural block. * Body mass index ≥ 35.

Locations (1)

Menoufia University Hospitals

Shibīn al Kawm, Menoufia, Egypt

RECRUITING

Outcomes

Primary Outcomes

pain relief

VAS score from 0 to 10 will be assesed

Time frame: at 30 min after induction of block

pain relief

VAS score from 0 to 10

Time frame: on delivery

Central Contacts

mostafa S mansour, MD

CONTACT

01225484055 mostafa.said@med.menofia.edu.eg

Data from ClinicalTrials.gov

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