The purpose of this retrospective study is to assess the treatment benefits of probiotic Streptococcus salivarius K12 for the prevention of recurrent bacterial and viral infections of the pharynx, tonsils and ears in children under 3 years of age.
Recurrent bacterial and viral infections of the pharynx, tonsils and ears are a problem that can affect children of all ages. The persistence of these infections can lead to an overuse of drugs such as antibiotics, antipyretics and anti-inflammatories, with the possible consequent presence of side effects and above all an increase in antibiotic resistance, a global public health issue. In search at reducing the use of antibiotics and antivirals, there is currently a great scientific interest in probiotic therapies for the oral cavity infection. The aim of this retrospective, controlled, multicenter, non-profit study is to evaluate the efficacy and safety of the administration of Streptococcus salivarius K12 in pediatric patients attending the 1st or 2nd year of nursery school (\< 3 years of age ), in the prophylaxis of the most common bacterial or viral respiratory infections, assessing the consequent reduction in the use of antibiotics, antivirals or other therapies compared to children.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
287
Oral 1 billion CFU of Probiotic Streptococcus salivarius K12
Children who did not receive any probiotic supplementation
Liaquat University Hospital
Jāmshoro, Pakistan
Incidence of any Gastrointestinal upset
Safety and tolerability of the probiotic treatment
Time frame: 03 Months
Bacterial or respiratory viral infection
Evaluation of the frequency of bacterial or respiratory viral infection
Time frame: 03 Months
Use of antibiotics or antivirals
Evaluation of the frequency of use of antibiotic or antiviral therapies
Time frame: 03 Months
Other pathologies
Evaluation of the frequency of incidence of other pathologies such as GI
Time frame: 03 Months
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