This study will compare the results of 24 h conservative treatment and N h conservative treatment of adhesive small bowel obstruction (where N = 72 h minus duration of intestinal obstruction).
Patients with acute adhesive intestinal obstruction, who dont need an emergency operation, will be given water insoluble contrast per os and randomized into two groups - early and delayed surgery. The first group will receive conservative treatment within no more than 24 h. Duration of non-operative treatment in second group will be 72 h minus duration of intestinal obstruction, based on the onset of symptoms. In both groups surgery will be performed if contrast will not reach colon in mentioned terms or clinical deterioration signs will appear. The results of 24 h conservative treatment and N h conservative treatment (where N = 72 h minus duration of intestinal obstruction) will be compared.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
180
Median laparotomy with subsequent detection of intestinal obstruction cause and adhesiolysis.
Plain X-ray of abdomen (1-4 times) with water insoluble contrast.
A set of measures aimed at non-operative resolution of acute intestinal obstruction - nasogastric tube, infusion therapy.
26 City Hospital
Saint Petersburg, Russia
RECRUITINGNorth-Western State Medical University named after I. I. Mechnikov
Saint Petersburg, Russia
RECRUITINGSaint-Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine
Saint Petersburg, Russia
Non-operative treatment success
Frequency of non-operative intestinal obstruction resolution
Time frame: 72 hours
Overall mortality
Number of patients, died during hospitalization
Time frame: up to 30 days
Postoperative complications
Number and variety of postoperative complications in patients, who underwent surgery
Time frame: up to 30 days
Resectional interventions
Number of patients, who underwent surgery, including small bowel resection
Time frame: up to 30 days
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The City Hospital of the Holy Martyr Elizabeth
Saint Petersburg, Russia
RECRUITING