The aim of our study was to compare the effects of Lomber Epidural Analgesia (LEA), Transversus Abdominis Plane (TAP) block and Local Anesthetic Infiltration (LAI) on postoperative morphine consumption, time to first recue analgesic request, pain and patient satisfaction scores and side effects were compared in the patients undergoing major gynecologic/oncology lower abdominal surgery.
Following faculty ethical committee approval and written informed consent, 81 patients were included in our prospective, randomized and double-blind study. Patients were divided into 3 groups: lumbar epidural block (Group E), TAP block (Group T), and wound infiltration (Group I). Demographic data, surgical characteristics, hemodynamic values, pain scores at rest and on movement, morphine consumption, additional analgesic requirement, side effects at 1, 2, 6, 12, 24, 36 and 48th hours after surgery, and patient satisfaction scores at 24 and 48th hours were recorded.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
81
postoperative analgesic method
postoperative analgesic method
postoperative analgesic method
Cukurova University
Adana, Turkey (Türkiye)
Cukurova University
Adana, Turkey (Türkiye)
morphine consumption
At the end of the surgery, the patients were allowed to use the patient controlled analgesia device (PCA). The PCA (CADD Legacy PCA pump, Smiths Medical MD, Inc. St. Paul, MN) was prepared with 40 mg morphine HCl in 100 ml saline. The PCA doses of morphine consisted of a bolus dose of 0.02 mg/kg every 15 minutes without a background infusion. Morphine consumption (mg) was evaluated and recorded postoperative 48 hours.
Time frame: change from baseline morphine comsumption at 48 hours
pain scores
postoperative pain scores of the patients were recorded using visual analog scale (VAS; 0=no pain, 10=worst pain)
Time frame: change from baseline pain scores at 48 hours
patient satisfaction score
patient satisfaction scores were recorded using patient satisfaction scale (0= worst, 10=excellent)
Time frame: postoperative 24 and 48 hours
time to first rescue analgesic
If the patients complained of pain despite the analgesia regimen, iv 50 mg meperidine was given as a rescue analgesic.
Time frame: postoperative 48 hours
side effects
all patients were visited after surgery in the ward and side effects were evaluated and recorded
Time frame: postoperative 48 hours
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.