Ninety adult patients from both gender, with acute respiratory failure, intubated and mechanically ventilated. Their ages ranged from 50 to 70 years. They were selected from Intensive Care Unit (ICU), Department of Chest Diseases, Cairo University Hospitals. They have randomly assigned into three equal groups. Group (A): trained by threshold IMT device plus routine physical therapy. Group (B): trained by adjusting MV trigger sensitivity plus routine physical therapy. Group (C): only received routine physical therapy. (Negative inspiratory force NIF, arterial blood gases, P/F ration, respiratory rate RR, tidal volume VT, and rapid shallow breathing index RSBI) were measured before the study and at the end of the study (just before weaning for successfully weaned patients, or on the 10 day of intervention for failed weaning patients).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Enrollment
90
The threshold inspiratory muscle trainer (IMT) device offers resistance to respiration through the spring-loaded valve.
modifying the mechanical ventilator trigger sensitivity so that patients can only initiate inspiratory flow by producing more negative intrathoracic pressure
Conventional chest physiotherapy
Faculty of Physical Therapy
Cairo, Egypt
partial pressure of oxygen(PaO2)
arterial blood sample was taken and examined thePao2
Time frame: change from baseline at one week
partial pressure of carbon dioxide(PaCO2)
arterial blood sample was taken and examined the PaCO2
Time frame: change from baseline at one week
Respiratory rate (RR)
Number of respiratory cycles per minute
Time frame: change from baseline at one week
tidal volume (TV)
volume of air inspired in quiet breathing
Time frame: change from baseline at one week
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