Heart failure (HF) is a chronic disease with an increasing incidence; it represents the final stage of multiple cardiac diseases and significantly affects the QoL of the patients. Its prevalence is about 26 million people in the world, especially in elderly. Sarcopenia has been directly associated with the presence of increased comorbidity in patients with HF. In this study the investigators aim to compare the clinical evolution of patients with HF after receiving nutritional support with Mediterranean diet alone or in combination with a hypercaloric, hyperproteic oral nutritional Supplement
All participants will receive general counseling, education about MedDiet and vitamin D supplementation in order to reach levels of sufficiency (25OH vitamin D\>30 ng/dL) for avoiding confounding results. Participants (n=50) will be randomly allocated to MedDiet or MedDiet plus hypercaloric, hyperproteic standard oral nutritional supplement (ONS), 2 ONS per da). Participants will be evaluated at baseline, 12 and 24 weeks after nutritional support
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
50
2 supplements per day
Mediterranean diet
IMIBIC
Córdoba, Cordoba, Spain
Muscle mass
Changes in percent of muscle mass
Time frame: 6 months
Left ventricular ejection fraction
Changes in left ventricular ejection fraction
Time frame: 6 months
pro-BNP
Changes in pro-BNP
Time frame: 6 months
Fat mass
Changes in fat mass using bioimpedance and echography
Time frame: 6 months
Phase angle
Changes in phase angle using bioimpedance
Time frame: 6 months
Albumin
Changes in serum albumin levels (g/l)
Time frame: 6 months
Preallbumin
Changes in serum prealbumin levels (mg/dl)
Time frame: 6 months
Transferrin
Changes in serum transferrin levels (mg/dl)
Time frame: 6 months
CRP
Changes in CRP levels (g/l)
Time frame: 6 months
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