Role of Early Point of Care Ultrasound in Management of Sepsis in Emergency Department

Alexandria University200 enrolled

Overview

Aim of the study is to determine the diagnostic accuracy of point-of-care ultrasound and to determine its role in sepsis management .

Two groups of patients will be studied one group will undergo POCUS examination and the other will not undergo POCUS examination then comparison between them will be done regarding accuracy of diagnosis and time taken to reach diagnosis.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

200

Conditions

Sepsis

Interventions

POCUS examinationDIAGNOSTIC_TEST

Point of care ultrasound examination

Eligibility

Sex: ALLMin age: 19 YearsMax age: 100 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adult patients admitted to the Emergency Department (ED) of Alexandria Main University Hospital (AMUH) with sepsis. * Patients presented with septic shock. Exclusion Criteria: * Age less than 18 * Trauma patients. * Pregnant females. * Patients with terminal malignancy. * Patients taking immunosuppressive drugs or chemotherapy.

Locations (1)

Alexandria main university hospital

Alexandria, Egypt

Outcomes

Primary Outcomes

Diagnostic accuracy of POCUS approach compared with the definitive diagnosis.

The study will include two groups of patients, POCUS group that will undergo point of care ultrasound (POCUS)examination in addition to clinical evaluation and laboratory investigations and control group that will not undergo POCUS examination but only undergo clinical evaluation and laboratory investigations. Both groups will be compared regarding proportion of accurate diagnosis (at emergency department)in relation to the final diagnosis that will be obtained after patient undergo further imaging techniques to search for sepsis such as chest X-ray or CT to look for chest infection and CT abdomen to confirm intra-abdominal sepsis. Unlike trauma, dyspnea and shock up till now there is no validated POCUS protocol to evaluate patients with sepsis.

Time frame: 8 months

Secondary Outcomes

Time taken to reach diagnosis in both groups

Evaluation of the difference between two groups regarding time taken to reach diagnosis

Time frame: 8 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.