The etiology of Goal B type basilar invagination (BI) is still not clear, and it may be related to platybasia and short slope. There is no unified standard surgical strategy for Goal B type BI, and different surgical strategies have a great influence on the surgical results of patients. The purpose of our prospective study in China is to (1) further clarify the etiology of Goal B type BI, and (2) improve the surgical outcome in these patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
200
Posterior fossa decompression:Posterior arch of atlas removal, decompression of cerebellum, detection of foramen magnum.
Posterior Compression-Distraction-Reduction-Fixation:After subperiosteal dissection, the facet joint was exposed. A 2-mm joint "scraper" with sharp edge was inserted into the joint capsule and rotated to remove the articular cartilage. A blunt-edged rotating distractor was then inserted into the joint space, and the facet was sequentially opened with larger and larger blunt rotating distractors. After distraction on one side, an appropriate-sized trial was placed into the contralateral facet, holding the distraction open. This was repeated back and forth with larger trials. These steps were repeated, and the facet joints were distracted up to the pre-planned distance of the odontoid tip above Chamberlain's line.
Xuanwu Hospital
Beijing, Beijing Municipality, China
RECRUITINGJOA Score(Japanese Orthopaedic Association Scores)
Changes in JOA score,from 0 to 17, higher scores means better outcome
Time frame: 1 months, 3 months, and 6 months postoperatively
NDI Score
Changes in NDI score,from 0% to 100%,higher scores means worse outcome
Time frame: 1 months, 3 months, and 6 months postoperatively
Change of Basilar Invagination
Radiographic assessment of the reduction of basilar invagination, using distance from odontoid tip to Chamberlain's line (DCL)
Time frame: 1 months, 3 months, and 6 months postoperatively
Change of CCA
Radiographic assessment of the change in clivus-canal angle (CCA)
Time frame: 1 months, 3 months, and 6 months postoperatively
Change of CVJ triangle area
Radiographic assessment of the reduction of CVJ triangle area
Time frame: 1 months, 3 months, and 6 months postoperatively
Change of CMA
Radiographic assessment of change of cervico-medullary angle (CMA)
Time frame: 1 months, 3 months, and 6 months postoperatively
Change of subarachnoid space
Radiographic assessment of the relief of width of subarachnoid space
Time frame: 1 months, 3 months, and 6 months postoperatively
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.