opioid free anesthesia consists of combination of pharmacological and non pharmacological modalities that target different pathways of pain mechanism. combining myofascial plane blocks with infusion of adjuvants such as lidocaine or dexmedetomidine can offer equivalent intraoperative hemodynamic stability compared to that of opioid with better pain control postoperatively. this study will investigate the efficacy of combined erector spina block with lidocaine and dexmedetomidine infusion as opioid sparing anesthesia in spine surgeries
patients who will undergo spine surgery will be allocated into two groups. after general anesthesia, bilateral erector spine block will be applied in both groups. group A will have intraoperative fentanyl infusion and group B will have lidocaine and dexmedetomidine infusion in 50 ml syringe till end of surgery
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
140
intraoperative opioid infusion in active comparative group
intraoperative non opioid infusion in experimental group
Ainshams hospitals
Cairo, Egypt
number of patients (percentage) having intraoperative systolic hypertension
blood pressure more than 160 mmhg
Time frame: during operation(intraoperatively)
number of patients(percentage) having tachycardia
heart rate more than 100 beat /minute
Time frame: during operation(intraoperatively)
VAS score
score from 0 to 10, 0 is no pain and 10 the worst pain
Time frame: every 30 minutes for 2 hours postoperatively
incidence of bradycardia
heart rate less than 45 beat per minute
Time frame: intraoperatively
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