The Effect of Post-extraction Collagen Sponge Application on Alveolar Osteitis

Riyadh Colleges of Dentistry and Pharmacy40 enrolled

Overview

The goal of this randomized controlled trial is to compare pain, mouth opening, and alveolar osteitis following surgical extraction of bilateral symmetrical impacted lower third molars using two types of wound closures. Collagen plugs will be applied in the sockets of the study side followed by suture, while the controlled side will be sutured without a collagen plug. The study will include 40 patients aged between 18- 40 years old, medically fit (ASA1), who have bilateral symmetrical impacted lower third molars and visit the oral surgery clinics of King Saud Medical City for extraction. The main question is" Does intra-alveolar collagen application after surgical extraction of impacted lower third molars reduce the incidence of alveolar osteitis?

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Alveolar Osteitis

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: Forty patients aged between 18- 40 years old, ASA1, who have bilateral symmetrical impacted lower third molars and visit the oral surgery clinics of King Saud Medical City for extraction. Exclusion Criteria: Uncontrolled systemic diseases, diabetes, bone diseases, smokers, epinephrine contraindications, pregnant women, breastfeeding women, and those who were using oral contraceptives. Other exclusion criteria are the presence of acute infection and facial swelling, cystic lesions, and TMJ problems. Moreover, any surgical extraction that lasts more than 30 minutes +/- 5 minutes, or has been done without the whole standardized steps will be excluded.

Outcomes

Primary Outcomes

Pre-extraction Pain score

Pain measurement by VAS (0-10). 0: no pain. 10: worst pain

Time frame: Pre-extraction

Pre-extraction Halitosis

Halitosis in reported in the presence of a bad odor that is smelled by the investigator during the patient's speech

Time frame: Pre-extraction

Pre-extraction Mouth opening

Maximum Mouth opening is taken by a caliber

Time frame: Pre-extraction

Pain score Day3

Pain measurement by VAS (0-10). 0: no pain. 10: worst pain

Time frame: 3 days after extraction

Pain score Day7

Pain measurement by VAS (0-10). 0: no pain. 10: worst pain

Time frame: 7 days after extraction

Mouth opening Day7

Maximum Mouth opening is taken by a caliber

Time frame: 7 days after extraction

Halitosis Day7

Halitosis in reported in the presence of a bad odor that is smelled by the investigator during the patient's speech

Time frame: 7 days after extraction

Alveolar osteitis

is diagnosed if the patient complains of pain (more than 5) between day 2 and day 4 with empty sockets and food debris, with or without halitosis

Time frame: After 3 days of extraction

The Effect of Post-extraction Collagen Sponge Application on Alveolar Osteitis

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Central Contacts