Efficacy of Dexmedetomidine VS Magnesium Sulphate With Bupivacaine in Erector Spinae Block for Thoracotomy Pain

National Cancer Institute, Egypt60 enrolled

Overview

Postoperative pain management is considered an integral part of perioperative care in patients undergoing thoracotomy. In order to reduce these complications, multiple regional techniques have been developed for thoracotomy including Intercostal nerve block, Erectospinae plane block and serratus block. Multiple adjuvants have been used in regional analgesia including adrenaline,clonidine,magnesium sulphate,dexmedatomidine and opoids.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Analgesia

Interventions

BupivacaineDRUG

Bupivacaine 0.25%

Bupivacaine + MagnesiumDRUG

Bupivacaine 0.25% + Magnesium

Bupivacaine + DexmedetomidineDRUG

Bupivacaine 0.25% + Dexmedetomidine

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age from 18 to 65 years. * Male and female sexes. * ASA I-II.,III * Cancer patients undergoing thoracotomy incisions * Body mass index (BMI) from 18.5 to 30 kg/m2 Exclusion Criteria: * Patient refusal * Known allergy to any of the used drugs * Low platelet count, any coagulation defect

Locations (1)

Walaa Y Elsabeeny

Cairo, Egypt

RECRUITING

Outcomes

Primary Outcomes

Total postoperative morphine consumption

Total dose of morphine needed postoperatively in the first 24 h

Time frame: First 24 hours postoperatively

Secondary Outcomes

Time to first postoperative rescue analgesia.

Time frame: First 24 hours postoperatively

Central Contacts

Walaa Y Elsabeeny, MD

CONTACT

01007798466 walaa.elsabeeny@nci.cu.edu.eg

Ahmed A Mohamed, MD

CONTACT

01272222923 ahmed.aboali7268@gmail.com

Data from ClinicalTrials.gov

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