Neuromuscular Ultrasonography Assessment of Optic Nerve in Systemic Lupus Eryhematosus

Amira M elSonbaty140 enrolled

Overview

assessing the role of neuromuscular ultrasound in optic nerve involvement in systemic lupus patients.

Evaluating the role of neuromuscular ultrasound in optic nerve involvement in systemic lupus patients.by measuring the diameter of optic nerve at certain site and comparing it to healthy subjects measurements and to asses NMUS ability to detect optic neuropathy in lupus patients in comparison to conventional techniques including opthalmologist evaluation and visual evoked potential

Study Type

OBSERVATIONAL

Enrollment

140

Conditions

Optic Neuropathy

Eligibility

Sex: ALLMin age: 17 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Adult * group of SLE patients, who fulfilled Systemic Lupus International Collaborating Clinics classification criteria for SLE (SLICC) with or without symptoms of optic neuropathy * another group of apparently healthy subjects with no. history of chronic conditions Exclusion Criteria: * Any patient with optic neuritis due to causes other than lupus was excluded from the study: ex. * Post traumatic neuropathy * Purely degenerative neuropathy * Diabetic neuropathy * Toxic neuropathy * Neuropathies related to infections * Drug induced neuropathy e.g: quinine and some antibiotics, ethambutol * Infections e.g. measles, mumps, Lyme disease, etc. * Other Autoimmune diseases like sarcoidosis, B.D * Tumor causing Inc. intracranial tension.

Locations (1)

Assuit university hospital

Asyut, Egypt

Outcomes

Primary Outcomes

comparing diameter (in mm2) of optic nerve in SLE patients and compare them to healthy subjects

Time frame: over 1 year

Data from ClinicalTrials.gov

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