The goal of this clinical trial is to evaluate the efficacy of screening for liver disease with liver stiffness measurement on abstinence or light consumption after 6 months in individuals who are receiving treatment for alcohol use disorder and without a history of liver disease. The investigators will conduct a randomized controlled trial with concealed allocation comparing A) an invitation to a liver stiffness measurement, blood sampling and leaflet on alcohol-related disease (intervention) with B) an invitation to blood sampling (control). The primary outcome is 'abstinence or light consumption' (≤ 10 units/week) throughout the last months, and assessed 6 months after randomization.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SCREENING
Masking
DOUBLE
Enrollment
408
One transient elastography 1-2 weeks after randomization
Novavi Køge
Køge, Denmark
RECRUITINGNovavi Roskilde
Roskilde, Denmark
RECRUITINGAlcohol abstinence or light consumption (≤ 10 units/week) the last 30 days (yes/no) assessed 6 months since randomization
Assessed By telephone interview or health record
Time frame: Assessed 6 months after randomization
Heavy drinking days last 30 days
Assessed by telephone interview or health record
Time frame: Assessed 6 months after since randomization
Change in AUDIT-C score (yes or no) since randomization
AUDIT: the Alcohol Use Disorders Identification Test is a validated manual for use in primary care to identify persons with hazardous and harmful patterns of alcohol consumption
Time frame: 6 months after randomization
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