Tranexamic acid in debridement surgery of burns on the volume of bleeding in transfusion requirements
A randomized, double-blind, prospective trial was conducted to establish the effect of intraoperative tranexamic acid in the early surgical debridement of severe burns. The study was carried out between the months of January 2022 and December 2023.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
20
10mg/kg intravenous single dose
100 ml intravenous single dose
Centro Médico Nacional de Occidente
Guadalajara, Jalisco, Mexico
RECRUITINGCompare the group with tranexamic acid with the group with saline solution.
The differences between the groups at the beginning of the study were evaluated with the Student's t test for continuous variables, and the proportions were compared with the Chi2 or Fisher test.
Time frame: The time frame: the total time of the study is during the first day, only one dose will be given, and they will be compared at 24 hours.
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