Dental implants may suffer from bone loss around them, particularly at the upper portion where the prosthesis starts. The connection between both parts of the tooth restoration is key for avoiding micromovement during chewing, bacterial contamination and initiation of bone loss. Thus, investigating factors related to this bone loss in different types of implant-prosthetic connections is key for promoting better use of available therapeutics devices. In this study, we will study marginal bone levels over time as well as bacterial contamination and inflammatory markers in the peri-implant sulcus around implants with connical connection and compare them with those obtained when using implants with internal hexagonal connection. The hypothesis is that bone loss will be higher in implants with hexagonal connection associated with a pathological microbiome in the sulcus that induces a higher inflammatory response.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
42
Placement and restoration of a single Ziacom Galaxy dental implant with internal connical prosthetic connection
Placement and restoration of a single Ziacom Zinic dental implant with internal hexagonal prosthetic connection
Universidad de Granada
Granada, Spain
RECRUITINGMarginal bone level
Time frame: 1 year
Peri-implant microbiome
Relative abundance of microbial species in the peri-implant sulcus evaluated by next-generation sequencing methods
Time frame: 1 year
Peri-implant inflammation
Concentration of pro-inflammatory markers in the peri-implant sulcus evaluated by multiplex techniques methods
Time frame: 1 year
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