Investigation on changes in the neurochemical stress parameters in acute stroke. 30 patients are recruited in the stroke unit, blood samples are collected at fixed intervals during the first two days. Patients are randomized to music listening and control.Neuropsychological testing is performed in the acute phase and 6 months post-stroke.
Outcome measures: NIHSS, stress hormone levels, questionnaires on mood and quality of life.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
32
Music listening under instruction by music therapist, min 3 hours daily
Standard treatment, care and rehabilitation
Turku University Hospital
Turku, Finland
Depression, Anxiety and Stress Scale
Change in Depression, Anxiety and Stress Scale scores
Time frame: 1 day post-stroke
National Institute of Health Stroke Scale
Change in National Institute of Health Stroke Scale scores
Time frame: 1 day post-stroke
Visual Analogue Mood Scale
Change in Visual Analogue Mood Scale scores
Time frame: 2 days post stroke
Serum cortisol
Change in serum cortisol level
Time frame: 2 days post-stroke
Serum C-reactive protein
Change in serum C-reactive protein level
Time frame: 2 days post-stroke
Montreal Cognitive Assessment
Montreal Cognitive Assessment score
Time frame: 3 days post-stroke
Blood pressure
Change in systolic/diastolic blood pressure
Time frame: 3 days post-stroke
Pulse rate
Change in pulse rate
Time frame: 3 days post-stroke
Depression, Anxiety and Stress Scale
Change in Depression, Anxiety and Stress Scale scores
Time frame: 6 months post-stroke
National Institute of Health Stroke Scale
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Change in National Institute of Health Stroke Scale
Time frame: 6 months post-stroke
Visual Analogue Mood Scale
Change in Visual Analogue Mood Scale scores
Time frame: 6 months post-stroke
Montreal Cognition Assessment
Change in Montreal Cognition Assessment score
Time frame: 6 moths post-stroke
Stroke and Aphasia Quality of Life scale
Change in Stroke and Aphasia Quality of Life scale score
Time frame: 6 months post-stroke
Center for Epidemiological Studies Depression score
Change in Center for Epidemiological Studies Depression score
Time frame: 6 months post-stroke
Working Memory Questionnaire
Change in Working Memory Questionnaire score
Time frame: 6 months post-stroke
Stroke Impact Scale
Change in Stroke Impact Scale score
Time frame: 6 months post-stroke
Leisure Activity Questionnaire
Change in leisure activities (pre- vs. post-stroke)
Time frame: 6 months post-stroke