The Efficacy and Safety of Dezocine Pretreatment for Pain Relief in Acne Scar Treatment of Fractional CO2 Laser
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE
Enrollment
105
All patients were given oral administration of 0.5mg paronosetron hydrochloride and lidocaine cream 1 hour before surgery. After cleaning and disinfection, fractional CO2 laser treatment was given. Among them, the fractional CO2 laser laser (American Medical Laser company) selected relatively constant energy parameters in the treatment
Desocine injection was injected intravenously half an hour before surgery (10ml normal saline was added for more than 30 seconds)
Dermatology Derpartment of Xijing Hospital
Xi'an, Shaanxi, China
RECRUITINGVisual Analog Score for Pain
0 was classified as painless and 10 was classified as unbearable pain. Marks were made on the corresponding parts of the ruler and scores were scored according to the degree of patient's feeling
Time frame: 24 hours
Hemodynamic parameters
diastolic blood pressure (DBP), systolic blood pressure (SBP)
Time frame: 24 hours
Heart rate (HR)
Hemodynamic parameters
Time frame: 24 hours
oxygen saturation (SpO2)
Hemodynamic parameters
Time frame: 24 hours
Occurrence of Adverse Reactions
Nausea, vomiting,dizziness,respiratory depression
Time frame: 24 hours
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