Predictors of Failure of Non-invasive Ventilation and High Flow Nasal Cannula

Assiut University120 enrolled

Overview

Comparison between some predictors of failure of non-invasive ventilation and high flow nasal cannula.

Delayed intubation after NIV / HFNC failure is associated with high mortality rate in acute respiratory failure patients. There are Many factors to predict early failure but World still searching for new factors and comparing between each ;in order to eatablish best one that achieve the least mortality rate. Little studies about effiecacy of HACOR Score as a predictor of failure in HFNC patients. Little studies about effiecacy of ROX Index as a predictor of failure in NIV ventilating patients.

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

Acute Respiratory Failure Patients on NIV and HFNC

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: Acute respiratory failure patients who need ventilatory Support either NIV or HFNC due to : 1. RR \> 25 cycle / min 2. using accessory muscles and paradoxical breath. 3. PaO2 / FiO2 ratio \< 300 Exclusion Criteria: 1. Absolute indication for intubation like coma, haemodynamically unstable… etc 2. Contr-indication of NIV like untreated Pneumothorax.

Outcomes

Primary Outcomes

Determine Golden time for intubation

Determine best time for intubation according to some predictors of failure of NIV and HFNC

Time frame: 1 year

Data from ClinicalTrials.gov

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