Pain Trajectories and Predictors After Noncardiac Surgery in Elderly Patients

Feng Gao300 enrolled

Overview

This study will use group-based trajectory modeling to identify the different postoperative pain trajectory groups that exist in a mixed surgical population (non-cardiac surgery) of elderly patients during the first seven days after surgery. The aim of this study is to explore the diversity in the development of postoperative pain among elderly patients and to identify the risk factors for acute pain trajectory after surgery by investigating demographic, psychological, and clinical variables. The predictive effect of different trajectories of early postoperative acute pain on postoperative chronic pain will also be explored.

Study Type

OBSERVATIONAL

Enrollment

300

Conditions

Acute Postoperative Pain Trajectory

Eligibility

Sex: ALLMin age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Scheduled for thoracic, urologic, gastrointestinal, gynecological, liver, biliary/pancreatic, or major orthopedic surgery under general anesthesia 2. Age ≥ 65 years 3. The American Society of Anaesthesiologists(ASA) I to III 4. Duration of hospitalization ≥ 72 hours Exclusion Criteria: 1. Language disorder; 2. Hearing impairment; 3. Visual impairment; 4. The expected postoperative intubation time is more than 24 hours; 5. Critical events occurred during the perioperative period.

Locations (1)

Outcomes

Primary Outcomes

Acute pain trajectories after surgery

The acute pain trajectories are vectors of 7 numerical pain scores (ranging from 0 ,which indicates "no pain," to 10 , which indicates "pain as bad as you can imagine") taken over 7 days (days 1, 2, 3, 4, 5, 6, 7).

Time frame: Seven days after surgery.

Presence of pain 3 months after surgery assessed using the Brief Pain Inventory.

Yes/No

Time frame: 3 months after surgery

Presence of pain 6 months after surgery assessed using the Brief Pain Inventory.

Yes/No

Time frame: 6 months after surgery

Secondary Outcomes

consumption of analgesic drugs

the amount of analgesic drugs will be recorded

Time frame: Seven days after surgery

cumulative illness rating scale for geriatrics，CIR S-G

The Cumulative Illness Rating Scale (CIRS) is utilized to assess comorbidities and comprises of 14 components, each with a severity score ranging from 0 to 4. A score of 0 indicates no damage, while a score of 1 denotes minor damage that does not impede normal activity and has a positive prognosis without treatment. A score of 2 indicates moderate damage, while a score of 3 denotes severe damage that may result in disability and necessitates immediate treatment with a poor prognosis. A score of 4 indicates fatal damage that requires urgent treatment and has a severe prognosis.