The purpose of this study is to confirm there is no significant effect of gastric pH changes of famotidine on the drug levels of afimetoran in healthy participants.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
76
Specified dose on specified days
Specified dose on specified days
Quotient Sciences
Nottingham, Nottinghamshire, United Kingdom
RECRUITINGMaximum observed plasma concentration (Cmax)
Time frame: Up to 20 Days
Time to attain maximum observed plasma concentration (Tmax)
Time frame: Up to 20 Days
Area under the plasma concentration-time curve from time zero to time of the last quantifiable concentration (AUC[0-T])
Time frame: Up to 20 Days
Number of participants with adverse events (AEs)
Time frame: Up to 52 Days
Number of participants with clinical laboratory abnormalities
Time frame: Up to 52 Days
Number of participants with vital sign abnormalities
Time frame: Up to 52 Days
Number of participants with electrocardiogram (ECG) abnormalities
Time frame: Up to 52 Days
First line of the email MUST contain the NCT# and Site #.
CONTACT
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