Effect of Platelet-rich Fibrin on Soft Tissue, Periodontal Pocket Healing and Alveolar Bone Height After Third Molar Surgery

Inclusion Criteria: * Patient over 18 years old. * Good general health. * Bilateral lower third molars equivalent in inclination and Pell and Gregory's impaction classification (classification II, III and B, C). The assessment of equivalence between two mandibular third molars was determined on the panoramic radiograph. * The difference of third molar inclination on both sides not greater than 15 degrees. * The patient consented to participate in the study after hearing clearly the explanation of purposes and requirements of the study. Exclusion Criteria: * Patients with any systemic disease contraindicated for surgery. * Presence of acute inflammation or infection at third molar areas. * Patients refused to participate in the study, did not comply with treatment or did not come to the follow-up examination as required. * The difference in surgical time between the two groups was more than 10 minutes.