The aim of this study is to determine whether krill oil supplementation enhances effects of a pragmatic resistance exercise programme on adaptations in muscle strength, mass, function and neuromuscular function in sedentary older adults. Hypothesis - krill oil supplementation will enhance the beneficial effects of resistance exercise on muscle strength, function, mass and neuromuscular function in sedentary older adults.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
60
Mixed vegetable oil
Superba Krill Oil
Home based resistance band and body weight exercise
University of Glasgow
Glasgow, United Kingdom
Nueromuscular Junction (NMJ) transmission instability
NMJ transmission instability will be measured by iEMG
Time frame: Change from baseline to 16 weeks
Knee extensor maximal torque
Knee extensor maximal torque will be measured by a load cell
Time frame: Change from baseline to 8 16 weeks
30s chair stand test
measuring the functional abilities
Time frame: Change from baseline to 16 weeks
Gait speed
measuring the functional abilities
Time frame: Change from baseline to 16 weeks
Force steadiness during submaximal isometric knee extensor contractions
Steadiness of force whilst contracting
Time frame: Change from baseline to 16 weeks
Red Blood Cell Omega-3 levels
Time frame: Change from baseline to 16 weeks
Grip strength
Grip strength will be measured by handgrip dynamometer
Time frame: Change from baseline to 16 weeks
Muscle thickness
Vastus Lateralis muscle thickness will be measured by ultrasound
Time frame: Change from baseline to 16 weeks
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