The purpose of this study is to test the hypothesis that the equivalent glycemic load (EGL) value of portions of white bread containing 5 g available carbohydrate measured in this study is accurate and precise to within 1 gram. Additionally, the EGL of 7 low carbohydrate foods will be measured to determine their glycemic impact.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
25
Food
INQUIS Clinical Research, Ltd.
Toronto, Ontario, Canada
Equivalent glycemic load
Equivalent glycemic load (EGL) for each test food, expressed as \[EGL = T/(W/Cwb)\] where T is the plasma glucose incremental area under the curve over 120 minutes (iAUC) elicited by one serving of test food, W is the mean iAUC elicited by the mean of two WB20 tests and Cwb is the amount of available carbohydrate in the WB20.
Time frame: -5 minutes to 120 minutes
Insulin iAUC over 120 minutes
Postprandial serum insulin incremental area under the curve over 120 minutes for each food in a subset of n=10 individuals. Blood will be collected at -5, 0, 15, 30, 45, 60, 90, and 120 minutes.
Time frame: -5 minutes to 120 minutes
Glucose iAUC over 120 minutes
Postprandial plasma glucose incremental area under the curve over 120 minutes for each food in n=25 individuals. Blood will be collected at -5, 0, 15, 30, 45, 60, 90, and 120 minutes.
Time frame: -5 minutes to 120 minutes
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.