The goal of this interventional study is to evaluate the effects of bundle combination of Amway All-plant protein booster with Nutrilite Lifestyle guideline and/or EMS (Electric Muscle Stimulation) device on Osteoarthritis \& Sarcopenia in the middle-aged and elderly (50-70 years old) people. 240 eligible participants will be randomly assigned to 4 equal size study groups (ideally 52 for each group will complete the study) in the two study centers in Shanghai, three site visits will be made during the 6 months of study after screening test. All clinical data will be measured /captured on paper CRF(Case Report Form) and then recorded into CTMS(Clinical Trial Data Management System) for analysis and reporting. It's essential that participants should practice with the assigned guideline and device besides taking the products per day. Researchers will compare the four groups to see if there is significant improvement of Amway study products with bundle combination of Nutrilite Lifestyle guideline and/or EMS on Osteoarthritis \& Sarcopenia in the participants.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Enrollment
240
All-plant protein booster: 2 spoons (15g), twice per day. Calcium \& Magnesium:3 tablets one time per day. Glucosamine: 2 tablets two times per day. 20 minutes training with EMS (Electric Muscle Stimulation) per day. Practice according to Nutrilite Lifestyle Guideline per day.
All-plant protein booster: 2 spoons (15g), twice per day. Calcium \& Magnesium:3 tablets one time per day. Glucosamine: 2 tablets two times per day. 20 minutes training with EMS (Electric Muscle Stimulation) per day.
Placebo: 2 spoons (15g), twice per day. Placebo for Calcium \& Magnesium:3 tablets one time per day. Placebo for Glucosamine: 2 tablets two times per day.
Placebo: 2 spoons (15g), twice per day. Placebo for Calcium \& Magnesium:3 tablets one time per day. Placebo for Glucosamine: 2 tablets two times per day. Practice according to Nutrilite Lifestyle Guideline per day.
Raison Healthcare Lab
Shanghai, Shanghai Municipality, China
Raison Healthcare R&D Center
Shanghai, Shanghai Municipality, China
Change of Short Physical Performance Battery (SPPB) score from baseline
Change of Short Physical Performance Battery (SPPB) score \[0,12\] from baseline to day 180
Time frame: baseline day 0, day 180
Change of WOMAC Questionnaire Scores from baseline
Change of WOMAC Questionnaire Scores from baseline to day 90 and day 180
Time frame: baseline day 0, day 90, day 180
Change of Visual Analogue Scale/Score (VAS) from baseline
Change of Visual Analogue Scale/Score (VAS), with range from 0 to 10 (the smaller the score, the better visual result), from baseline to day 90 and day 180
Time frame: baseline day 0, day 90, day 180
Change of Chalder Fatigue Scale (CFS) from baseline
Change of Chalder Fatigue Scale (CFS), FS-14, with range from 0 to 14 (the bigger the score, the more fatigue a person feels), from baseline to day 90 and day 180
Time frame: baseline day 0, day 90, day 180
Improvement of Fat and Muscle Portions measured by Inbody S10 from baseline
Improvement of Fat and Muscle Portions measured by Inbody S10 from baseline to day 90 and day 180
Time frame: baseline day 0, day 90, day 180
Change of Hand & Grip Strength measured by Jamar Smart Hand Dynamometer from baseline
Change of Hand \& Grip Strength measured by Jamar Smart Hand Dynamometer from baseline to day 90 and day 180
Time frame: baseline day 0, day 90, day 180
Change of bone density measured by DXA Bone Densitometer from baseline
Change of bone density measured by DXA Bone Densitometer from baseline to day 90 and day 180
Time frame: baseline day 0, day 90, day 180
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.