This study is to investigate whether the improvement or maintenance of cognitive function is superior to the control group when gum chewing is performed in elderly people with subjective cognitive decline or mild cognitive impairment.
The intervention group chew one unscented gum provided by the study for 12 weeks. Using KakaoTalk, the coordinator sends a chewing gum alarm. The participants are instructed to masticate a gum for 20 minutes every day, alternately for 10 minutes on the right side and 10 minutes on the left side. After chewing gum, they perform masticatory muscle stretching and tongue exercises. After they finish chewing the gum, he or she reports completion by posting an authentication photo in the KakaoTalk chat room. The research coordinator checks the certification on a weekly basis and sends a separate phone call to encourage participants who do not chew gum more than twice a week.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
94
chewing gum everyday for 12 weeks. Alternate chewing for 10 minutes on the right and 10 minutes on the left.
Bobath Memorial Hospital
Seongnam-si, Gyeonggi-do, South Korea
RECRUITINGInha University Hospital
Incheon, South Korea
RECRUITINGEwha Womans Seoul Hospital
Seoul, South Korea
RECRUITINGChange of cognition
Repeatable Battery for the Assessment of Neuropsychological Status (range 40-160). Higher scores indicate better performance.
Time frame: Change from Baseline at 12 weeks
Change of global cognition
Korean Mini-Mental State Examination-2 (range, 0-30). Higher scores indicate better performance.
Time frame: Change from Baseline at 12 weeks
Change of function
Clinical Dementia Rating scale-Sum of Boxes (range 0-18). Higher scores indicate worse performance.
Time frame: Change from Baseline at 12 weeks
Change of depression
Geriatric Depression Scale-15 items (range 0-15). Higher scores indicate worse mood.
Time frame: Change from Baseline at 12 weeks
Change of activities of daily living
Bayer Activities of Daily Living (range 1-10). Higher scores indicate worse performance.
Time frame: Change from Baseline at 12 weeks
Change of quality of life
Quality of life-Alzheimer's disease (range 0-52). Higher scores indicate better performance.
Time frame: Change from Baseline at 12 weeks
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Ajou University Hospital
Suwon, South Korea
RECRUITING