Fine particulate matter \<2.5 µm (PM2.5) air pollution is the fifth leading risk factor for global mortality, with the largest portion of deaths due to cardiovascular disease (CVD). While several mechanisms are responsible, PM2.5-induced elevations in blood pressure (BP) may be relevant. Indoor portable air cleaners (PACs) are a novel approach to reduce exposure to PM2.5 and potentially lower blood pressure. The current study is being conducted to provide evidence that PACs reduce PM2.5 exposure and lower systolic blood pressure (SBP) in key patient populations.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
440
The active PAC will contain HEPA filters inside the device.
The sham PAC will contain no HEPA filters inside the device.
NYU Langone Health
New York, New York, United States
RECRUITINGAverage Self-Measured Morning Home Systolic Blood Pressure (AM H-SBP) over 30 Days
Participants measure HBP every day between 6-9 am.
Time frame: Up to Day 30
Average Self-Measured Morning Home Systolic Blood Pressure (AM H-SBP) over 90 Days
Participants measure HBP every day between 6-9 am.
Time frame: Up to Day 90
Average Self-Measured Morning Home Systolic Blood Pressure (AM H-SBP) over 180 Days
Participants measure HBP every day between 6-9 am.
Time frame: Up to Day 180
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