Methotrexate Iontophoresis Versus Coal Tar Ointement in the Treatment of Primary Palmer Hyper Hidrosis

Inclusion Criteria: * Patient with primary palmar hyperhidrosis to extend that their palms are wet during most of the day (score 3 and 4 in the Hyperhidrosis Disease Severity Scale) was included in this study. * The palmer hyperhidrosis patient's age ranged from 15 to 35 years. * All patients will be examined by dermatologist before starting the study. Exclusion Criteria: The study excluded the following patients: * Patients with medical conditions that associated with hyperhidrosis are excluded, these conditions include:- hyperthyroidism, diabetes mellitus, parkinsonism, spinal cord injury, brain damage, congestive heart failure, anxiety, alcoholism and menopause. * Patients who received any treatment with a drug that was affecting sweating e.g. (thyroxin, anxiolytics…..) that is not stopped at least 4 weeks preceding the study. * Patients with cardiac conditions such as arrhythmia, ischemic heart disease, low exercise tolerance, low respiratory reserve were excluded. * Patients, who have a local wound, sever eczema and severe fungal infection of the palms to minimize risk of local burn. * Patients who have sensory disorders. * Female patients who are pregnant and lactating.