MRI T1 Relaxation Time in Rectal Cancer

Vejle Hospital44 enrolled

Overview

The goal of this observational study is to learn about the T1 relaxation time and T1 relaxation time properties of the disease in people with locally advanced rectal cancer. The main question it aims to answer is: Does MRI T1 relaxation time have a high diagnostic performance in recognizing fibrosis as a complete response to neoadjuvant treatment of rectal cancer? Participants will receive standard neoadjuvant treatment and be part of the standard examination programme regarding rectal cancer.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Rectal Cancer Locally Advanced Rectal Carcinoma

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * rectal cancer, age \>18 years Exclusion Criteria: * contraindications for MRI (pacemaker, claustrophobia, implanted medical injectors and nerve stimulators), * previous radiochemotherapy or another disease which investigator judges inappropriate for the persons continued participation.

Locations (1)

Vejle Hospital

Vejle, Jylland, Denmark

Outcomes

Primary Outcomes

Difference in T1 relaxation time (ms) in the rectal cancer tumor measured in IntelliSpace-software before and after neoadjuvant radiochemotherapy.

An MRI T1 relaxation time-map is performed on each participant. The data is transferred to IntelliSpace-software for measurement and mapping. It is measured in miliseconds (ms) before and after neoadjuvant treatment.

Time frame: 6 to 8 weeks.

Data from ClinicalTrials.gov

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