Mindfulness-oriented Recovery Enhancement (MORE) for Cancer Pain Relief

Phase 2Active Not RecruitingNCT05877521

Memorial Sloan Kettering Cancer Center76 enrolled

Overview

The purpose of this study is to evaluate whether or not mindfulness-based interventions/MBIs may help reduce chronic pain in participants who have cancer-related chronic pain. MBIs are therapeutic programs that use mindfulness meditation practices to help people focus on the present moment, as well as encourage acceptance of thoughts, emotions, and body sensations. The researchers think that an MBI treatment called Mindfulness-oriented Recovery Enhancement (MORE) may help people who are experiencing cancer-related chronic pain.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Chronic Pain Cancer Pain

Interventions

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * English speaking * Age ≥ 18 years or older * A history of cancer with no restrictions placed on type of cancer * Determined to be either no-evidence of disease or stable oncological disease by referring or study physicians/advanced practice providers * Having a pain (musculoskeletal, generalized, or neuropathic) rating of 4 or greater in worst pain on a 0-10 numerical rating scale in the preceding week * Having had pain for at least 3 months and at least 15 days with pain in the preceding 30 days * Willing to adhere to all study-related procedures, including randomization to one of two treatment arms: MORE or WLC * Ability to attend video-call session and a quiet/private location Exclusion Criteria: * Active suicidality or schizophrenia * Plan to initiate palliative radiation or interventional pain procedure within the next 12 weeks * Cognitive impairment preventing completing PRO independently or participate in virtual MORE as evaluated by study clinicians

Outcomes

Primary Outcomes

Rate of participant enrollment to the study

Feasibility of the intervention will be determined by Rate of participant enrollment to the study

Time frame: 12 months