The goal of this clinical trial is to evaluate the efficacy, safety and tolerability of lactulose in bowel preparation in IBD patients. The main question it aims to answer is: Does lactulose have better efficacy, safety and tolerability than 3L-PEG? Participants will be divided into PEG group or Lactulose group at a 1:1 ratio by a random number method. Each patient will get a leaflet provided by hospital introducing bowel preparation methods and diet restriction before bowel preparation. They will have bowel preparation with different drugs according to group. The grade of bowel cleansing will be assessed through the Boston Bowel Preparation Scale (BBPS). The tolerability, satisfaction and safety of the two bowel preparation methods will be assessed through the patients self-administered questionnaires.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
140
Patients will take lactulose for bowel preparation.
Patients will take 3L-polyethylene glycol for bowel preparation.
The Second Affiliated Hospital of Wenzhou Medical University
Wenzhou, Zhejiang, China
effective preparation rate
Boston Bowel Preparation Scale (BBPS) \>= 6 with a partial score \>= 2 in each colon segment
Time frame: 5 minutes before the colonoscopy ends
incidence of adverse events
incidence of adverse events in each group
Time frame: 2 hours after having bowel preparation
taste score evaluated by patients
Five-point scale is used to evaluate taste (very bad, bad, moderate, good, very good)
Time frame: 2 hours after having bowel preparation
effects of bowel preparation drugs on liver function
total protein, albumin, bilirubin, alanine aminotransferase
Time frame: 2 hours after having bowel preparation
effects of bowel preparation drugs on serum electrolyte
sodium, potassium, chloride
Time frame: 2 hours after having bowel preparation
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