In previous attemps to answer the question of risk-benefit of postpartum thromboprophylaxis, researchers were faced with low recruitement rates. The goal of this pilot feasibility randomized controlled trial of postpartum pharmacological thromboprophylaxis is to examine the feasibility (recruitement rate) and participation rate at the Geneva University Hospitals
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
77
Prophylactic dose of enoxaparin once daily for 10 days after delivery.
Geneva University Hospitals
Geneva, Switzerland
Recruitement rate
Number of study inclusion per month
Time frame: 6 months
Study participation
Proportion of eligible women who are presented the study and who accept to participate
Time frame: Within 48 hours after delivery
Venous thromboembolism
Pulmonary embolism and deep vein thrombosis
Time frame: Within 90 day after delivery
Bleeding
Major and clinically relevant non-major bleeding
Time frame: Within 90 day after delivery
Surgical site complication
Cesarean section site complication
Time frame: Within 90 day of delivery
Heparin-induced thrombocytopenia
Time frame: Within 90 day of delivery
Septic pelvic thrombophlebitis
Time frame: Within 90 day of delivery
All-cause mortality
Time frame: Within 90 day of delivery
Satisfaction with study intervention
Satisfaction based on TSQMII questionnaire
Time frame: After completion of the 10 days of study drug
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