The goal of this clinical trial is to Determine efficacy of intermittent enteral nutrition vs continuous enteral nutrition in adults patients with a nasogastric tube in a intensive care unit. The main question\[s\] it aims to answer are: * Reduction of gastrointestinal and respiratory complications * Evaluate the achievement of the caloric objective Informed consent will be requested from participants who meet the inclusion criteria. The participants will be randomized into two groups: control group (continuous enteral nutrition) or experimental group (intermittent enteral nutrition) Researchers will compare intermittent enteral nutrition vs continuous to see if there is a reduction in gastrointestinal and respiratory complications.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
190
Administration of Enteral Nutriton (EN) by nasogastric tube in 4 bolus (24h): Duration of the infusion 1hour each shot, using an infusion pump.
Administration of Enteral Nutriton (EN) by nasogastric tube during 24 hours, using an infusion pump.
Maria Dolores Saiz Vinuesa
Albacete, Spain
RECRUITINGRespiratory Complications
Respiratory aspiration of gastric content
Time frame: during ICU stay (maximum 15 days)
Gastrointestinal Complications
Digestive intolerance: Diarrhea, vomiting, increased gastric residual volume(GRV)
Time frame: during ICU stay (maximum 15 days)
Achievement of the caloric objective
Time in hours to reach caloric goal
Time frame: during ICU stay (up to 15 days)
Nutritional status: MNA
Measure with:Mini Nutritional Assessment,(MNA) 12-14 points: Normal nutritional status 8-11 points: risk of malnutrition 0-7 points: Malnutrition
Time frame: up to two days after admission to the ICU
Changes in blood glucose
Episodes of hypoglycemia or hyperglycemia
Time frame: during ICU stay (maximum 15 days)
ICU Stay
Days of stay in ICU
Time frame: From date of randomization until 100 months
Mortality
Percentage of deaths in ICU
Time frame: until the date of death from any cause until 100 months
Change of type of EN administration
Change of EN administration modality
Time frame: during ICU stay (maximum 15 days)
Nutritional status:Glim Criteria
Measure with: Glim criteria: Phenotypic criteria:Non-volitional weight loss (%) Low BMI (kg/m2)Reduced muscle mass(calf circumference (cm)) Etiologic criteria: Reduced food intake or assimilation. Inflammation \*Requires at least one phenotypic criterion and one etiologic criterion for the diagnosis of malnutrition
Time frame: up to two days after admission to the ICU
Nutritional status: Biochemical values
Measure with:biochemical values: albumin, prealbumin, total protein
Time frame: up to two days after admission to the ICU
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