Development and Validation of a Risk Prediction Model for Preoperative Frailty in Elderly Patients With Colorectal Cancer

Inclusion Criteria: 1. patients who met the diagnostic criteria of colorectal cancer in Chinese Guidelines for Diagnosis and Treatment of Colorectal Cancer 2020 Edition and underwent surgery; 2. patients aged ≥60 years old ; 3. patients who are clearly conscious, able to understand instructions, communicate normally, and complete the physical activity ability test without the assistance of others; 4. patients who gave informed consent and volunteered to participate in the study. Exclusion Criteria: 1. patients with limb joint disease and lower limb pain; 2. patients with serious heart, liver, kidney diseases could not complete the test; 3. patients with visual impairment and hearing impairment; 4. patients with a history of mental illness or drug dependence; 5. taking antidepressants, levodopa/carbidopa, donepezil hydrochloride and other drugs ; 6. patients who received preoperative radiotherapy and chemotherapy; 7. Patients with hypothyroidism, Parkinson's disease, stroke and other diseases.