GIC-102, Intravenous Allogeneic NK Cells, in Subjects With Advanced Solid Cancers and R/R Hematologic Malignancies

Inclusion criteria: 1. At least 19 years of age 2. Advanced solid tumors, relapsed/refractory non-hodgkin lymphoma, and multiple myeloma 3. At least one measurable or evaluable lesion 4. Eastern Cooperative Oncology Group performance status 0 or 1 5. A life expectancy of 12 weeks or more 6. Acceptable hematological function, kidney, and liver function 7. Subjects who sign on an informed consent form willingly Exclusion Criteria: 1. Clinically significant cardiovascular disease within 24 weeks 2. Primary malignant tumor other than the indications for this study 3. The following diseases 1. Severe infection or other uncontrolled active infectious disease requiring administration of systemic antibiotics or antivirals within 4 weeks 2. The New York Heart Association class III/IV 3. Active hepatitis B virus or hepatitis C virus infection 4. Human immunodeficiency virus positive 5. Clinically significant symptoms or uncontrolled central nervous system metastasis 4. Previously been diagnosed with immunodeficiency or need systemic corticosteroids or other systemic immunosuppressants within 2 weeks or require administration of systemic immunosuppressants during the study 5. Received chemotherapy other than pre-conditioning within 4 weeks 6. Underwent major surgery within 4 weeks prior or minor surgery within 2 weeks 7. Hypersensitivity reactions to the study drug or excipients 8. Hypersensitivity to cyclophosphamide or fludarabine 9. Have received allogeneic cell therapy within 6 months or autologous stem cell therapy within 4 weeks 10. Have previously received an allogeneic tissue/solid organ transplant 11. Have administered other investigational drug or applied other investigational medical device within 4 weeks 12. Pregnant or lactating female subjects 13. Male subjects who did not agree to use contraception or to maintain abstinence