Intercostal cryoanalgesia is a technique that allows extensive and prolonged analgesia of the hemithorax. The aim of this study is to demonstrate the efficacy of intercostal cryoanalgesia as an adjunct to a single-injection paravertebral block for the prevention of chronic thoracic pain after VATS lung resection surgery.
VATS lung resection is associated with a high incidence of persistent thoracic pain. To our knowledge, there is no study on the effect of cryoanalgesia on the incidence and severity of chronic thoracic pain 3 months after VATS lung resection. Intercostal cryoanalgesia is a technique that allows extensive and prolonged analgesia of the hemithorax. In a recent study by Ilfeld \& al, intercostal cryoanalgesia (combined with a single-injection paravertebral block) was able to drastically lower the incidence of chronic pain after total mastectomy compared to the use of the paravertebral block alone (3% vs 17%). The aim of this study is to demonstrate the efficacy of intercostal cryoanalgesia for the prevention of chronic thoracic pain after VATS lung resection surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
80
CO2 Cryoanalgesia AND paravertebral block with Bupivacaine 0.5%
Paravertebral block with Bupivacaine 0.5%
Centre Hospitalier de l'Universite de Montreal
Montreal, Quebec, Canada
Incidence of persistent thoracic pain
Persistent postoperative thoracic pain (yes or no)
Time frame: 3 months
Incidence of persistent thoracic pain
Persistent postoperative thoracic pain (yes or no)
Time frame: 1 and 6 months
Severity of persistent thoracic pain
Numerical Rating Scale (NRS) score : scale 0 (no pain) to 10 (worst), at rest and during cough
Time frame: 1,3 and 6 months
Incidence of persistent opioid consumption
Persistent postoperative opioid consumption (yes/no)
Time frame: 1,3 and 6 months
Incidence of postoperative neuropathic pain
DN4 score (10 points) ; positive if 4 points or more
Time frame: 48 hours, 1 month and 6 months
Incidence of new prescription for neuropathic pain medication
Yes or no
Time frame: 1, 3 and 6 months
Persistent hypoesthesia over the ipsilateral thorax
Evaluation of the dermatomal levels of hypoesthesia using a Von Frey monofilament as well as the subjective presence of a sensation of hypoesthesia.
Time frame: 1 and 6 months
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.