Timing of Resistance Exercise in Type 1 Diabetes

Dasman Diabetes Institute54 enrolled

Overview

The aims of the current study are 1. to compare the effects of acute morning and afternoon resistance exercise on blood glucose levels in people with type 1 diabetes. 2. to compare the effects of morning and afternoon resistance exercise training on cardiometabolic health outcomes in people with type 1 diabetes

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Type 1 Diabetes

Interventions

Morning exerciseBEHAVIORAL

Between 6-10am participants will attend the gym and perform 10 min of warm up exercise, 3 sets of 7 resistance exercises ( leg press, calf press, leg curl, chest press, lateral raise, seated row and plank)

Afternoon exerciseBEHAVIORAL

Between 4-8pm participants will attend the gym and perform 10 min of warm up exercise, 3 sets of 7 resistance exercises ( leg press, calf press, leg curl, chest press, lateral raise, seated row and plank)

Habitual physical activity levelsBEHAVIORAL

Participants will be asked to maintain their normal activity levels

Eligibility

Sex: ALLMin age: 21 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Physician confirmed type 1 diabetes for at least 1 year * Stable insulin therapy for 3 months prior to the study Exclusion Criteria: * BMI of 45 or higher * BP of 160/100mmHg or higher * autonomic neuropathy * severe proliferative retinopathy * joint or limb injuries preventing weight-bearing activity * autonomic neuropathy * severe proliferative retinopathy * any other medical condition that prevents participants from exercising safely.

Locations (1)

Dasman Diabetes Institute

Kuwait City, Kuwait

RECRUITING

Outcomes

Primary Outcomes

Change in muscle strength

Sum of one repetition maximum for the 7 resistance exercise

Time frame: Change from baseline to 12 weeks

Change in interstitial glucose time in range

Interstitial glucose time in range (3.9-10mmol/L) measured via continuous glucose monitoring

Time frame: Change from 6 hours before (baseline) to 6 hours after (post-exercise) an exercise training session

Secondary Outcomes

Change in appendicular skeletal muscle mass

Measured by DEXA

Time frame: Change from baseline to 12 weeks

Change in whole body fat mass

Measured by DEXA

Time frame: Change from baseline to 12 weeks

Change in physical function

Measured by the short performance physical battery

Time frame: Change from baseline to 12 weeks

Change in HbA1c

HbA1c concentration

Time frame: Change from baseline to 12 weeks

Change in interstitial glucose average

Interstitial average glucose measured via continuous glucose monitoring

Time frame: Change from 6 hours before (baseline) to 6 hours after (post-exercise) an exercise training session

Change in interstitial glucose variability

Interstitial glucose variability measured via continuous glucose monitoring

Central Contacts

Ebaa AlOzairi, MBChB

CONTACT

+965 22242999 ebaa.alozairi@dasmaninstitute.rog

Data from ClinicalTrials.gov

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